July 10, 2014

Publication of Structural Basis for Smoothened Receptor Modulation and Chemoresistance to Anticancer Drugs in the journal Nature Communications
MORE >>

May 1, 2014

Two publications of the human P2Y12 receptors in the journal Nature
Agonist-bound P2Y12
MORE >>
Antagonist -bound P2Y12
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April 21, 2014

Review on allosteric role of sodium in class A GPCR signaling in TiBS on-line
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March 23, 2014

Publication of Structure of the human P2Y12 receptor in the journal Nature
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March 6, 2014

Publication of Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 in the journal Science
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January 12, 2014

Publication of Molecular Control of δ-Opioid Receptor Signalling in the journal Nature
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December 20, 2013

Publication of Serial Femtosecond Crystallography of G-Protein-Coupled Receptors in the journal Science
MORE >>

September 12, 2013

Publication of structure of the Human CCR5 Chemokine G-protein-coupled Receptor in the journal Science
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July 17, 2013

Publication of Structure of the Human Glucagon Class B G-protein-coupled Receptor in the journal Nature
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May 1, 2013

Publication of structure of the Human Smoothened Receptor in the journal Nature
MORE >>

March 21, 2013

Publication of two Serotonin receptors structures 5-HT1B
and 5-HT2Bin the journal Science

Serotonin 5-HT1B >>
Serotonin 5-HT2B >>

March 19, 2013

GPCR Dock 2013 closed 3/2/2013. Results forthcoming this Summer, 2013

January 24, 2013

GPCR Dock 2013 starts February 1st.
Spread the word and Register NOW at>>

November 26, 2012

SAB meetings for JCIMPT and GPCR Network to plan for the future.

August 24, 2012

Due to repeated requests for figures and artwork, popular items are being made available to the community for use. You can download them HERE>>

August 1, 2012

Congratulations TSRI graduate student
Eugene Chun on receiving the 2012 Margaret C. Etter student award from the BioMacromolecular Special Interest Group at ACA for his work on the membrane protein (GPCR) fusion toolchest

July 13, 2012

GPCRs as allosteric machines controlled by sodium, cholesterol, lipids, water in Science

June 5, 2012

New Fusion Protein Toolbox for membrane protein structural biology in Structure

May 17, 2012

Special issue of Nature highlighting all four opioid receptor crystal structures
kappa_opioid >>
mu_opioid >>
nociceptin >>
delta_opioid >>

March 21, 2012

Publication of kappa-opioid receptor structure in the journal Nature
For details click HERE >>

February 17, 2012

Publication of S1P1 receptor structure in the journal Science
For details click HERE >>

January 19, 2012

Biased Signaling Pathways in β2-Adrenergic Receptor Characterized by 19F-NMR - in Science Express
READ MORE >>

January 12, 2012

TiPS review on GPCR structural diversity and modularity
READ MORE >>

September 23, 2011

GPCR Network and JCIMPT-Complexes announce their Center and Scientific Advisory Board meetings to be held November 28-29, 2011 at TSRI

August 3, 2011

Wednesday, August 3, 2011 - PSI:Biology GPCR Network structure researchers hold first annual GPCR Network meeting.

June 22, 2011

In an international collaboration with the Iwata laboratory, the human Histamine H1 receptor structure solved with 1st generation antihistamine.
MORE >>

May 12, 2011

GPCR Network Assessment Opens - ligand selection for opioid receptor MORE >>

March 10, 2011

Agonist bound structure of the A2A adenosine receptor highlights “conformationally selective agonist” published in Science Express. more >>

Movie >>

November 19, 2010

The structures of the human chemokine CXCR4 and dopamine D3 are reported in Science
CXCR4 Structure >>
D3 Structure >>

November 17-18, 2010

3rd Annual NIH Roadmap to High Resolution Membrane Protein Structures Meeting to be held in La Jolla.
In addition, a special LCP hands on tools workshop will be held November 16th at the Scripps Research Institute led by Professor Vadim Cherezov.
For information, see more>>

October 7, 2010

5 structures of human CXCR4 chemokine GPCR published in Science more>>

September 14, 2010

GPCR Network established as a part of the NIH PSI:Biology program. For more information, see more>>

July 30, 2010

GPCR Dock 2010 assessment now closed to depositions, results to be announced in the early fall. For more information, please see more>>

June 4, 2010

GPCR Dock 2010 announced to evaluate the progress of GPCR modeling and docking in CXCR4 and D3 receptors. For more information, please see more>>

>February 1, 2010

3rd Annual NIH Roadmap meeting for membrane protein technologies Nov 17-18th in La Jolla more>>

> January 22, 2010

In collaboration with colleagues at UCSD and Leiden University,
structure based discovery of novel chemotypes for Adenosine A2A receptor antagonists more>>

> January 8, 2010

In collaboration with colleagues at Scripps Florida, dynamics of the human β2-adrenergic receptor revealed by hydrogen-deuterium exchange more>>

> June 1, 2009

Analysis of the GPCR Dock 2008 assessment is published in Nature Reviews Drug Discovery
more>>

> April 23, 2009

Scientists from the Stevens lab and Cravatt lab in collaboration with Pfizer,
Inc. discovered a potential new painkiller.
more>>

> January 16, 2009

Membrane Protein Postdoctoral Research Associate position available immediately more>>

> October 2, 2008

The Stevens Lab determined a 2.6 A structure of the human adenosine A2a receptor.
more>>

> June 11, 2008

The Stevens Lab established a Cholesterol Consensus Motif in GPCRs. more>>

> October 25, 2007

The Stevens Lab solved a high-resolution structure of the human beta2-adrenergic receptor in collaboration with Kobilka Lab from Stanford University.